Currently there are clinical trials around the world being undertaken in many neurology fields including;
- Peripheral Neuropathy
- Muscular Dystrophy
- Incomplete Spinal Cord Injury
These trials can take between 5 and 10 years to come to fruition, however the overwhelming understanding and results thus far are proving very successful. At Cellf we have studied these treatments and applied what we believe to be the most beneficial, non-invasive and safe protocols as our range of therapies. For more information please look at the many web sites available.
Cellf endeavours to help our patients to make informed decisions and offer the “Pros and Cons” in our full patient consultation process.
“An update on stem cell therapy for neurological disorders: cell death pathways as therapeutic targets”
by Sydney Corey, Shaila Ghanekar, Jake Sokol, John H. Zhang and Cesar V. BorlonganEmail author
Here, we compiled ten papers detailing recent strides in the field of stem cell therapy, which address critical issues relevant to pursuing this experimental treatment for clinical applications in brain disorders. Topics include efficacy, safety, and mechanism of action underlying cell therapy, emerging technologies and combination pharmacotherapies with cell transplantation directed at improving the functional outcomes, and evaluation of key translational components of advancing novel therapeutics to the clinic, including the need for vis-à-vis comparisons with the gold standard of treatment post-injury (i.e., physical rehabilitation). A bioethics paper is also incorporated here to further appreciate the current status of cell therapy in the community setting. The overall goal of this special volume is to provoke a meaningful assessment of the lessons we have learned in recent years and to use such knowledge to carefully translate safe and effective applications of cell therapy, and its mechanism of action for the treatment of neurological disorders.
In summary, these ten selected articles from the recent ASTNR meeting highlight the potential applications for stem cell therapy in neurological disorders, detailing the laboratory evidence on the safety, efficacy, and mechanism of action of these transplantable cells, altogether forming the basis for the clinical trials [30, 31, 32, 33]. Given the prevalence of stroke, many patients would greatly benefit from novel treatments that capitalize on the promising therapeutic benefits of stem cells. Numerous studies referenced throughout the articles have indicated the potential capability of stem cell therapy in regenerating the diseased brain. We are gaining more insights into the cellular death pathways mediating stroke [34, 35, 36, 37, 38, 39], and in parallel exploiting these novel disease-related mechanisms as therapeutic targets for stem cells to exert their functional benefits. Yet, these developing technologies face obstacles, such as bioethical concerns and misrepresentations, as well as exploitations by the unscrupulous media and business sector, preventing them from reaching full beneficial capacity. Accordingly, a common theme resonating throughout these papers is a push to increase translational research of cell-based therapeutics for clinical applications that will allow scientifically sound assessments of cell therapy, delineating hype from hope [40, 41, 42, 43, 44, 45, 46, 47, 48]. Forthcoming updates on the ongoing clinical trials of cell therapy will provide valuable information on which to build the future of stem cell research and therapeutic applications.
Feel free to contact us at Cellf for more information on neurology.
It is important to remember that although “Cell Regeneration Therapy” is an outpatient procedure and has been seen as a viable treatment to help soothe symptoms of pain, Cellf can neither predict or guarantee success for individual patients who undergo the Therapies. There are potential risks associated with any medical procedure. Please discuss this with a medical practitioner prior to undergoing any procedures.